Bone marrow sea-blue histiocytes in a case of ITP

Sea-blue-colored histiocytes associated with bone marrow granulomas.

A 77-year-old man was admitted for evaluation of pancytopenia. His blood examination revealed hemoglobin 9.7 g/dL, platelet count 149 3 10/L, and white blood cell count 3.2 3 10/L with normal differential. Peripheral blood smear showed red blood cells with anisocytosis, microcytes, and teardrop-shaped cells. There was mild leukopenia with relative monocytosis and normal platelets. Bone marrow b...

Sea-blue histiocytes and Gaucher cells in bone marrow of patients with chronic myeloid leukaemia.

A retrospective study of 211 bone marrow aspirates from patients with chronic myeloid leukaemia (CML) was undertaken to assess the incidence of Gaucher cells and sea-blue histiocytes. A significant correlation between the presence of these cells and prolonged survival was seen. Such storage histiocytes occurred most often during periods of relapsed chronic phase. This study shows that Gaucher c...

Sea-blue histiocytes in bone marrow aspiration sample: what is the importance?

Hansen's fingerprints in bone marrow histiocytes

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 47-year-old man from a region endemic for leprosy presented with a 1-month history of high grade fever and red, raised skin lesions on the upper limbs. He had multiple tender papules and nodules on his forearm and thigh along with sensory loss and thickeni...

Sea blue histiocytosis: a common abnormality of the bone marrow in myelodysplastic syndromes.

AIMS To determine whether myelodysplastic syndromes (MDS) are associated with sea blue histiocytosis in the bone marrow. METHODS A retrospective review of bone marrow aspirates from 35 patients presenting consecutively with MDS and from 20 patients with each of the following: normal marrow appearance (routine staging for non-Hodgkin's lymphoma), polycythaemia rubra vera, immune thrombocytopen...